10/12/2025
NEWS

New open-access milestone from uCAIR

“Broadband coherent Raman microspectroscopy for the investigation of head and neck cancer advancing ultrafast spectral histopathology” by Carl Messerschmidt Matteo Calvarese MohammadSadegh Vafaeinezhad Oleg Ryabchykov Anna Mühlig Tobias Meyer-Zedler Michael Schmitt Orlando Guntinas-Lichius Thomas Bocklitz Juergen Popp now published in Springer Nature’s Discover Imaging journal!

Coherent Raman scattering (CRS) imaging is moving from nice-to-have to need-to-have in cancer diagnostics – and our latest publication shows why.

Key highlights:
• Strong discrimination capability across patient tissue samples
• First proof-of-concept AI-based classification model
• High-speed imaging with a 134 µs dwell time – an order of magnitude faster than comparable multiplex CARS setups
• A major step towards ultrafast spectral histopathology and real-time diagnostics

📚 Open science: paper & data
Dive into the full open-access article here.
All supporting data are available upon request on Zenodo here.

Contact

Coordinator - University of Limerick
Dr. Christophe Silien

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uCAIR is funded by the European Union’s Horizon Europe research and innovation programme under Grant Agreement no. 101135175.