“Broadband coherent Raman microspectroscopy for the investigation of head and neck cancer advancing ultrafast spectral histopathology” by Carl Messerschmidt Matteo Calvarese MohammadSadegh Vafaeinezhad Oleg Ryabchykov Anna Mühlig Tobias Meyer-Zedler Michael Schmitt Orlando Guntinas-Lichius Thomas Bocklitz Juergen Popp now published in Springer Nature’s Discover Imaging journal!
Coherent Raman scattering (CRS) imaging is moving from nice-to-have to need-to-have in cancer diagnostics – and our latest publication shows why.
Key highlights:
• Strong discrimination capability across patient tissue samples
• First proof-of-concept AI-based classification model
• High-speed imaging with a 134 µs dwell time – an order of magnitude faster than comparable multiplex CARS setups
• A major step towards ultrafast spectral histopathology and real-time diagnostics
📚 Open science: paper & data
Dive into the full open-access article here.
All supporting data are available upon request on Zenodo here.

Coordinator - University of Limerick
Dr. Christophe Silien